Progesterone to Estrogen Ratio Calculator

Disclaimer:

The Progesterone to Estrogen Ratio Calculator is designed to provide a general estimation based on user-input values and selected units of measurement. This tool is intended for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment.

While we strive to ensure accuracy, the calculations and conversion factors used in this tool are based on general assumptions and may not account for individual variations or specific medical conditions. For personalized medical advice or to interpret your hormone levels accurately, please consult with a qualified healthcare professional.

The developers of this calculator make no guarantees regarding the accuracy or completeness of the information provided and are not responsible for any errors, omissions, or consequences arising from the use of this tool.

For more details about progesterone to estrogen ratio, check this study and this study.

Author Bio

Idris Ya’u

BSc Botany, MSc Biology

What is the correct ratio of progesterone to estrogen?

The optimal ratio of progesterone to estrogen is considered to be between 100:1 to 200:1 (progesterone: estrogen). This balance helps maintain hormonal harmony in the body, preventing symptoms related to hormone imbalances such as estrogen dominance.

For more details about the correct Progesterone to Estrogen Ratio, check here and here.

What happens when estrogen is higher than progesterone?

When estrogen is higher than progesterone, it leads to estrogen dominance. This condition can cause symptoms like weight gain, bloating, irregular periods, mood swings, headaches, and increased risk of conditions like fibroids or endometriosis.

Find more details about this question from this study and this study.

What is the normal range for estrogen and progesterone?

Estrogen: Normal ranges vary depending on the phase of the menstrual cycle:
Follicular phase: 20-200 pg/mL
Ovulatory phase: 150-750 pg/mL
Luteal phase: 30-450 pg/mL
Progesterone:
Follicular phase: 0.1-0.7 ng/mL
Ovulatory phase: 2-25 ng/mL
Luteal phase: 5-20 ng/mL

These ranges can vary slightly based on the lab and individual characteristics. You can learn more about estrogen progesterone normal range from this study and this study.

What are the symptoms of low progesterone to estrogen ratio?

When there is a low progesterone to estrogen ratio (estrogen dominance), you may experience:

Irregular or heavy periods
Breast tenderness
Mood swings or irritability
Fatigue
Weight gain, especially around the hips and thighs
Difficulty sleeping or insomnia
Anxiety or depression
PMS symptoms

Can you get pregnant with low estrogen and progesterone?

It may be difficult to get pregnant with low levels of estrogen and progesterone. Both hormones play a crucial role in preparing the uterus for implantation and maintaining a healthy pregnancy. Low estrogen can affect ovulation, while low progesterone may prevent successful implantation or cause early miscarriage.

What happens if you take progesterone without estrogen?

If you take progesterone without estrogen, it may help in conditions where estrogen dominance is an issue, such as during perimenopause or postmenopause. In women with a uterus, progesterone alone can help counterbalance estrogen to prevent uterine lining overgrowth (endometrial hyperplasia). However, taking progesterone without estrogen inappropriately may cause side effects like mood changes, weight gain, or sleep disturbances.

What are the symptoms of high progesterone?

High progesterone levels can cause symptoms such as:

Fatigue
Mood swings or depression
Dizziness
Bloating
Breast tenderness
Weight gain
Increased body temperature

Some women may experience sleep issues or reduced libido as well.

Do you need more estrogen or progesterone to get pregnant?

Both estrogen and progesterone are essential for getting pregnant:

Estrogen helps build up the uterine lining and triggers the release of an egg (ovulation).
Progesterone maintains the uterine lining after ovulation, ensuring it is thick enough for implantation and supporting early pregnancy.

Therefore, a balance of both hormones is needed to conceive and maintain a pregnancy.

How does the woman feel when estrogen is high?

When estrogen is high, women may feel:

Breast tenderness
Bloating
Mood swings
Anxiety or irritability
Headaches or migraines
Weight gain, especially in the hips and thighs

In some cases, women may experience fluid retention or a reduced sex drive.

How can I balance my estrogen and progesterone levels?

To balance estrogen and progesterone levels, consider the following:

Diet: Eat more fiber, cruciferous vegetables (e.g., broccoli, cauliflower), and avoid processed foods.
Exercise: Regular physical activity helps regulate hormones.
Reduce stress: High stress increases cortisol, which can disrupt progesterone production.
Manage weight: Excess fat can produce more estrogen.
Herbal supplements: Supplements like Vitex (chasteberry) or Maca root may help balance hormones.
Hormonal therapy: If necessary, consult with a doctor about bioidentical hormone replacement therapy (BHRT) to address imbalances.

Reference

Yang Y, Liu B, Wu G, Yang J. Exploration of the value of progesterone and progesterone/estradiol ratio on the hCG trigger day in predicting pregnancy outcomes of PCOS patients undergoing IVF/ICSI: a retrospective cohort study. Reprod Biol Endocrinol. 2021 Dec 11;19(1):184. doi: 10.1186/s12958-021-00862-6. PMID: 34893087; PMCID: PMC8665570.
Giersch GEW, Charkoudian N, Morrissey MC, Butler CR, Colburn AT, Caldwell AR, Kavouras SA, Casa DJ. Estrogen to Progesterone Ratio and Fluid Regulatory Responses to Varying Degrees and Methods of Dehydration. Front Sports Act Living. 2021 Oct 14;3:722305. doi: 10.3389/fspor.2021.722305. Erratum in: Front Sports Act Living. 2022 Feb 10;4:848595. doi: 10.3389/fspor.2022.848595. PMID: 34723178; PMCID: PMC8551666.
The influence of estradiol and progesterone on neurocognition during three phases of the menstrual cycle: Modulating factors
Cable JK, Grider MH. Physiology, Progesterone. [Updated 2023 May 1]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK558960/
Sex-specific Estrogen Levels and Reference Intervals from Infancy to Late Adulthood Determined by LC-MS/MS
Moya-Salazar J, Cerda SP, Cañari B, Moya-Salazar MM, Contreras-Pulache H. Reference intervals of the sex hormonal profile in healthy women: A retrospective single-center study in Peru. Heliyon. 2022 Sep 8;8(9):e10592. doi: 10.1016/j.heliyon.2022.e10592. PMID: 36119895; PMCID: PMC9475304.

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Progesterone to Estrogen Ratio Calculator